Posts

What should one's policy regarding dental xrays be? 2021-09-17T20:55:15.701Z
What are good resources for gears models of joint health? 2021-06-06T17:39:50.303Z
The BTC equilibriumating and the ETH one-eightening 2021-05-25T21:32:20.604Z
Will Martian G be enough to make healthy baseline babies? 2021-03-09T03:30:46.583Z
Reasonable ways for an average LW retail investor to get upside risk? 2021-02-16T19:44:17.277Z
Have you tried hiIQpro.com's cognitive training or coaching? 2020-09-13T22:05:23.421Z

Comments

Comment by Randomized, Controlled (BossSleepy) on The Best Software For Every Need · 2021-09-20T00:09:08.155Z · LW · GW

...Interesting. Why do you prefer it?

Comment by Randomized, Controlled (BossSleepy) on What should one's policy regarding dental xrays be? · 2021-09-20T00:06:40.214Z · LW · GW

But, discounting institutional knowledge out of hand is foolhardy.

Is it? I feel like dentistry seems similar to sports science and physiotherapy in addressing super complex evolving gibs of soft and hard tissue. My general impression is that sports and physio research is marginally better than dentistry, which leaves the state of research clear enough to declare it... kind of abysmal. But also to show that a lot of practitioners swear by isn't well supported by evidence. Much of Ingraham's painscience.com is devoted to scrutinizing physio standards of care w/r/t the state of research..

I honestly don't know how to square this with practitioners who always seem confident in their assessments and make rote noises about being evidence based, and then even have reasonable sounding noises when I ask probing questions.

Comment by Randomized, Controlled (BossSleepy) on What should one's policy regarding dental xrays be? · 2021-09-19T16:30:50.773Z · LW · GW

I think this is a pretty compelling point, but:

  • How well understood is the dental health/heart disease connection? I've heard this assertion before, including from in the classic Interventions for Longevity post, but do we know if it's causal?
  • 98% survivable sounds.. goodish, but: what sort of quality of life hit do you take?

As I mentioned above, I'm still leaning towards okaying the imaging, but also think the default policy of every two years they use may be too aggressive for me, given the absence of any cavities up till now.

Comment by Randomized, Controlled (BossSleepy) on What should one's policy regarding dental xrays be? · 2021-09-18T14:21:41.858Z · LW · GW

A different way of saying this is: power (dE/dt) may be important.

Comment by Randomized, Controlled (BossSleepy) on Bayeswatch 9: Zombies · 2021-09-12T16:39:33.150Z · LW · GW

I really appreciate your exegesis of these.

Comment by Randomized, Controlled (BossSleepy) on Bayeswatch 9: Zombies · 2021-09-12T12:57:59.441Z · LW · GW

I read it as: unleash the z-day AI which we already know how to counter, but which will attract the attention of the new AI, allowing us to the the neutrino beacon to locate the new AI.

Comment by Randomized, Controlled (BossSleepy) on Bayeswatch 9: Zombies · 2021-09-11T19:31:58.147Z · LW · GW

I always looks forward to your fiction, but the Bayeswatch world is starting to feel a little... underpainted? Your prose and plotting style remind me of William Gibson and Peter Watts, who both tend to use the chopped sentences, jump cuts and elision, but they also spend a lot of effort building up so they they can then effectively cut back.

Concrete eg: you just placed a bunch of story action in Iran, but the number of locale specific details was thin: 'Natanz', 'Sherine Fakhrizadeh', 'the Israelis'.

Comment by Randomized, Controlled (BossSleepy) on The Best Software For Every Need · 2021-09-10T20:03:12.701Z · LW · GW

PythonDebuggerPlusPlus

Alternative: pdb, ipdb

Just pip install once into a venv and you'll get autocomplete in a pdb session and if you turn on sticky mode (which can be globally done via a config file) you'll get a proper display of the source code you're stepping thru.

Comment by Randomized, Controlled (BossSleepy) on The Best Software For Every Need · 2021-09-10T20:01:29.340Z · LW · GW

PromptToolkitIpython [Python shell]

Alternatives: python, ipython, jupyter

Jupyter notebooks are great for certain workflows where you're doing exploratory analysis but also want repeatability, but they're also clunkier and heavier than a shell session. ptpython has really good autocomplete and UI widgets. Ipython is an acceptable substitute.

Comment by Randomized, Controlled (BossSleepy) on The Best Software For Every Need · 2021-09-10T19:57:28.600Z · LW · GW

Ag: the silver searcher, (grep replacement)

Alternatives: grep, ack

Ack has a better interface than grep and ag is like ack but faster.

Comment by Randomized, Controlled (BossSleepy) on Conflict in Kriorus becomes hot today, updated, update 2 · 2021-09-09T22:10:30.374Z · LW · GW

What's your confidence in that succeeding? What would you consider success?

One measure that occurs to me is that a biological version of you and a digital version of you would both agree that the digital version is an accurate or faithful or acceptable translation.

Comment by Randomized, Controlled (BossSleepy) on Conflict in Kriorus becomes hot today, updated, update 2 · 2021-09-09T19:35:32.218Z · LW · GW

Via life-logging?

Comment by Randomized, Controlled (BossSleepy) on Conflict in Kriorus becomes hot today, updated, update 2 · 2021-09-08T22:26:44.517Z · LW · GW

Valeria took neuropatients (including my mother's brain)

Oh my god, I'm so sorry you and your mother are personally caught up in this. How horrifying.

Comment by Randomized, Controlled (BossSleepy) on Vaccination with natural immunity · 2021-08-18T16:18:18.350Z · LW · GW

A meta point: korin43 has done pretty well below trying to offer up a helpful reply, but in general you might get better responses by asking one or more specific questions; all you've done here is enumerate some facts: you've had covid; you don't have a diagnosis; there are some recommendations that may be relevant to you; you're worried; therefore... should I do...? Are there things I should research...? etc.

Comment by Randomized, Controlled (BossSleepy) on Predictions about the state of crypto in ten years · 2021-08-08T17:08:36.341Z · LW · GW

my secondary goal was to be as specific as I could.

If by "specific" you mean something like, "crisp and unambiguously able to be judged as resolving either yea or nay", you could sharpen these up more. They feel closer to being maxims, and more driven by the desire to not be laughable in 10yrs rather than the desire to be clear predictions. Eg:

An investor friend of mine said, “I think ETH had tons of exciting tech potential a few years ago, but little enough is being done on it that I don’t really see how it will keep its valuation unless there’s a new building boom or it happens to slide into store-of-value territory with BTC.”

Sounds plausible to me. In 2015 I was really confident that we would have at least one good platform for prediction markets by now. Augur is bad and polymarket is okay. I have to admit that I have been chronically overoptimistic.

What is "bad". What is "okay". I don't know that much about Eth's development process, but most projects move fast when they're young and obscure and slower when they're incumbents and have lots of value already embodied in them -- competitors to Eth can be expected to experience similar dynamics, whether they surpass Eth or not.

I feel more than 75% confident that in 10 years, a majority of my friends' and my family members are personally relying on at least one smart contract, even if they don’t deeply understand it or interact with it directly.

What does "relying on" mean -- they use an app that in someway interacts with a bChain? They use an app that interacts with an app that uses a bChain? Etc..

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-21T01:37:04.946Z · LW · GW

Also, for FWIW, while I don't have ChristianKI's level of education in movement, I am an experienced mediator, have done a reasonable amount of work with body scans and some work with tuning the motor cortex and three years of pretty serious contact improv dancing prior to lockdown. I think my proprioception is likely better than average, altho I'm not super confident in that, nor do I have a good sense if it's 60th or 90th percentile.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-19T16:09:35.664Z · LW · GW

I hope your Dad is doing OK.

He's dying. Likely going into palliative soon.

I have quite a lot to say about the link you provided, so will be back with a separate comment. Have you worked through "DAMN-IT" (from one of my previous comments) and seen where that gets you?

Yeah, informally. I don't really have a lot. I saw a physiatrist a few weeks ago, she felt there may be a little arthritis in the joint, but it wasn't the main problem.

I've got an order from my GP for blood work, including looking for markers of systemic inflammation, but haven't had a chance to fill it yet. In general I don't feel like I'm very inflamed -- my other joints don't really have a lot of issues (well.. a bit of tendency to rotator cuff soreness from climbing, but it generally seems well managed).

I lost a lot of leg strength with lockdown, bec I lost access to bit barbells, which has been shown to be a risk factor for knee pain. I've been working on rebuilding hip flexor and abductor strength, altho more in the high-reps/body-weight range.

There was no major mechanical incident or change; I'm pretty careful with my diet (like, careful enough to worry about omega-6/3 ratios, and to eat sardines a couple of times a week. I don't really eat industrially processed or produced foods, except for tofu, which is a staple and canned beans).

They seem to respond well to icing and voltarine, which makes me slightly more confident in the "low grade inflammation" theory.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-19T02:31:38.490Z · LW · GW

Hi. Apologies for not following up sooner -- my dad's been in the hospital.

Muscle tissue blending with connective tissues is very hard to describe in full detail but, ignoring the pelvic floor for a minute, the other 4 main muscles are big and easy to palpate. We know their attachment points to bone and connective tissue structures (minor variations in individuals have been noted and no doubt there are more that have not).

The is enough information for someone to find the muscles on their own body, to touch them and increase conscious awareness of them.

Okay. Abs, butt, quads, traps. I'll try being more mindful of those, and see if anything suggestive appears. But I also feel like Dr Scott Dye's failure-of-homeostatis model is more specific to what I'm going through ATM, and gears-y and prescriptive.

Seeing live/freshly dead tissues, feeling them in your hands, is a very different experience from learning from a textbook, histology slides or studying bodies prepared for dissection. They can't compare in giving understanding of how a body is put together, of what it really consists of. These experiences give me lot of confidence in what I say about the role of connective tissues, also the knowledge that defining and delineating is very difficult so I'm stic

This honestly sounds amazing. Is there a way for a civilian to get access to large mammal [human?] dissections? I'm assuming med schools don't just let you enroll in a single course or audit the anatomy offerings?

Thank you for the interaction! It's very useful.

Thank you for your engagement : )

Comment by Randomized, Controlled (BossSleepy) on You should ask for a third-party audit of your cryopreservation · 2021-07-09T00:02:31.073Z · LW · GW

Wouldn't the preservee have to provide their consent for this ahead of time? I've recently signed up for Alcor, I'd be very pro this being an option they explicitly offer to their customers.

Comment by Randomized, Controlled (BossSleepy) on Relentlessness · 2021-07-08T18:14:53.410Z · LW · GW

I think this is more or less how you make programmers. "Oy! You can read documentation? Here's a ticket, here's the office slack, best of luck friend!"

Comment by Randomized, Controlled (BossSleepy) on New Dementia Trial Results · 2021-07-06T19:56:28.721Z · LW · GW

Gah. My diet is pretty heavily leans on oats and rice as staples. Boooo.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-06T16:09:05.299Z · LW · GW

However, anatomy is much more fixed. Grossly examinable and recordable. Studied in detail for hundreds of years. We have accurate atlases of how the body is put together, what attaches where....

Anatomy may be more or less fixed, but our understanding of it is definitely much more fluid, and it seems possibly still pretty incomplete: apparently we've recently discovered enough new gross anatomical facts that an overview article was published on them in 2019.

I know I am right. It has taken a lot for me to get to the point of saying that out loud.

Putting aside the issue of levels of certainty here, I'd agree with ChristianKl that I'm a bit unclear what the implications of your model are, except perhaps, "pay attention to your posture and movement" which I already do a fair amount.

Comment by Randomized, Controlled (BossSleepy) on New Dementia Trial Results · 2021-07-06T15:43:15.290Z · LW · GW

Diet was a plant-rich, high-fiber, mildly ketogenic diet, high in leafy greens and other non-starchy vegetables (raw and cooked), high in unsaturated fats..

PeterMcCluskey, do you know any further specifics on the diet involved?

Comment by Randomized, Controlled (BossSleepy) on The Apprentice Thread · 2021-07-06T02:37:06.342Z · LW · GW

Likewise.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-05T21:30:44.955Z · LW · GW

There's not much in it but - based on my experiences and the anatomical facts - I am more certain about Base-Line Theory of Health and Movement that I am about the sun coming up tomorrow. There I've said it. It's what I believe. That strongly. Even so, I would be willing to change my mind and that's why I persevere with looking for feedback.

I'd also say that, just on a basic level, this is poor calibration. I would put "sun doesn't rise tomorrow" at... 1 in 10 million? 1 in 100 million? Maybe those are even too high, 1 in 10 million events do happen with some frequency, but maybe I'm just fundamentally deluded about the nature of reality right now. If my understanding of history and physics isn't completely borked, I'd be comfortable pushing that probability down to below 1 in a billion or lower.

I'm also comfortable predicting at 90% certainty that a majority of other LWers would also have probabilities for sun-doesn't-rise tomorrow below 1 in 1 million.

These are.. like.. real brute facts about reality kinds of things. General relativity. Newtonian mechanics. QM. Nuclear physics. That's the kind of foundation you can build 1 in 100 million-ish certainty on. Stuff with biology is in an entirely different realm of (un)certainties.

Comment by Randomized, Controlled (BossSleepy) on The Apprentice Thread · 2021-07-05T17:49:18.829Z · LW · GW

Curious why people have been downvoting this comment. Thanks for the recs. I already have read several of these and have some of them on my to read list, but some are new.

Comment by Randomized, Controlled (BossSleepy) on New Dementia Trial Results · 2021-07-04T16:30:36.822Z · LW · GW

Treatment protocol from the preprint:

Patients were treated for nine months with a personalized, precision medicine protocol that addressed each patient’s identified potentially contributory factors, and cognition was assessed at t = 0, 3, 6, and 9 months. The goal was to identify and address the factors associated theoretically and epidemiologically (though in some cases yet to be proven causally) with Alzheimer’s-related cognitive decline: restore insulin sensitivity, improve hyperlipidemia, resolve inflammation if present (and remove the cause(s) of the inflammation), treat pathogens, optimize energetic support (oxygenation, cerebral blood flow, ketone availability, and mitochondrial function), optimize trophic support (hormones, nutrients, and trophic factors), treat autoimmunity if identified, and detoxify if toxins were identified.

The treatment team included a health coach, nutritionist, and a physical trainer, as well as the physician.

Diet was a plant-rich, high-fiber, mildly ketogenic diet, high in leafy greens and other non-starchy vegetables (raw and cooked), high in unsaturated fats, with a fasting period of 12-16 hours each night. Organic produce, wild-caught low-mercury fish (salmon, mackerel, anchovies, sardines, and herring), and modest consumption of pastured eggs and meats were encouraged, as well as avoidance of processed food, simple carbohydrates, gluten-containing foods, and dairy. Blood ketone levels were monitored with fingerstick ketone meters, with a goal of 1.0-4.0 mM beta-hydroxybutyrate.

Exercise both aerobic and strength training, was encouraged for at least 45 minutes per day, at least six days per week, and facilitated by the personal trainers. High-intensity interval training (HIIT) was recommended a minimum of twice per week.

Sleep hygiene was supported to ensure 7-8 hours of quality sleep per night, and all patients without known sleep apnea were tested over several nights using home sleep study devices. In those diagnosed with sleep apnea or upper airway resistance syndrome (UARS), referral for treatment with a continuous positive airway pressure apparatus (CPAP) or a dental splint device (for those identified with UARS) was provided.

Stress management included biofeedback and heart-rate variability training with a HeartMath Inner Balance for IOS device, for a minimum of 10 minutes per day.

Brain training was carried out using BrainHQ, a HIPAA and SOC-2-compliant platform with empirical validation18, for a minimum of 15 minutes daily. Participants trained on 29 cognitive exercises that target the speed and accuracy of information processing. Hormones and nutrients

For those patients with suboptimal hormonal status, bio-identical hormone replacement and appropriate supplements were provided to optimize sex hormone levels, neurosteroids, and thyroid medications as indicated for sub-optimal thyroid function. For those with suboptimal nutrients (e.g., vitamin D, omega-3, B vitamins, CoQ10, or minerals), the appropriate nutrients were provided. Gastrointestinal health

For those with gastrointestinal hyperpermeability, infections, inflammation, or impaired absorption and digestion, gut healing with dietary restriction, gut-healing nutrients, and digestive enzyme support if indicated, along with treatment of any identified dysbiosis, was undertaken. Inflammation

For those with evidence of systemic inflammation, pro-resolving mediators and anti-inflammatory herbal supplements were provided, low-dose naltrexone was prescribed (if there was evidence of autoimmunity), and omega-3 fats included via diet and supplements. Some patients utilized fasting-mimicking diets.

Infectious agents associated with cognitive decline or systemic inflammation were identified and treated. For those with evidence of Herpes simplex infection or a history of outbreaks, valacyclovir was prescribed for 2-6 months. Active Epstein-Barr Virus (EBV) was treated with herbal protocols. For those with evidence of tick-borne infections such as Borrelia, Babesia, or Bartonella, organism-sensitive treatment was prescribed with herbal anti-microbials and immune support. Toxins and toxicants

For those with toxicity associated with metals (e.g., mercury or lead), organic pollutants (e.g., benzene, phthalates, or organophosphate insecticides), or biotoxins (e.g., trichothecenes, ochratoxin A, or gliotoxin), targeted detoxification was undertaken with binding agents (e.g., cholestyramine or bentonite clay), sauna, herbs, sulforaphane, and dietary restriction of seafood if indicated.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-07-04T12:55:26.568Z · LW · GW

Paul Ingraham has written pretty extensively on posture and it's relationship to pain/dysfunction, surveying the literature and concludes that there's very little evidence to support a posture/pain connection.

Comment by Randomized, Controlled (BossSleepy) on The Apprentice Thread · 2021-06-29T02:59:33.481Z · LW · GW

Testimonials could form part of this system. Mentee provides a testimonial that mentor is knowledgeable on the subject, able to communicate that knowledge, able to help someone progress, etc. This is both useful prestige and evidence of valuable skills.

Comment by Randomized, Controlled (BossSleepy) on D&D.Sci(-Fi) June 2021: The Duel with Earwax · 2021-06-23T02:21:58.962Z · LW · GW

If someone wanted to work on this collaboratively or just let me watch you work for a bit, HMU! I'm an experienced programmer, but fairly inexperienced with data analysis.

Comment by Randomized, Controlled (BossSleepy) on Scaling Networks of Trust · 2021-06-23T00:55:41.491Z · LW · GW

It's been about 15 years since I read Samuel Delany's Times Square Red, Times Square Blue, but I read it multiple times and wrote a paper or two which were heavily influenced by it.

This post reminded me of it. You might find it an interesting read. Times Square Red, the second half, is about strong and weak social networks (particularly in urban environments) and how they function.

Just a heads-up: the first half is quite sexually graphic -- it's a pretty explicit memoir of Delany's time in the Times Square porn theaters and the subculture of gay/homosocial sex and relationships that flourished there. It's pretty raunchy : )

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-22T17:53:13.625Z · LW · GW

standard markers of inflammation, ESR, CRP, etc. Or you could even look for the curve of cortisol response and clotting factors with a venous catheter, I guess. But again, not at all relevant outside of an academic curiosity unless you are training to be an athlet (which is unhealthy and should be avoided).

Are you implying I shouldn't [overly] worry about chronic inflammation? I'm pretty confident there is an inflammatory component here -- icing and voltaran do seem to help. It's been long enough (3 months) that I've started to think about trying a curcumin supplement and/or just cooking with tumeric+black pepper a bunch.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-22T00:42:45.340Z · LW · GW

No, it's really very much about your individual body and where you have lacks, you need an in-person trainer to be able to see this and over time as you move more you'll become more aware of your body and be able to say "Ah, it's x area that's too stiff, or activating too much, or that should be working but isn't or whatever"

Thank you for the info! Do you have any thoughts on how to evaluate a trainer's ability to discern this sort of thing? I'm happy to work with trainers and pay for expertise, but my general sense is that standards of research in sports medicine aren't great.

Comment by Randomized, Controlled (BossSleepy) on The Apprentice Thread · 2021-06-21T01:35:24.109Z · LW · GW

[Apprentice] I'm interested in this, may be over committed at the moment, but would really enjoy an intro chat.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-19T22:54:37.114Z · LW · GW

Stability training [evidence: not good because everyone disagrees what exactly this involves, but basically all physiotherapists are doing some form of stability training so it's obviously useful | overall you can pick a specific older technique and you will get solid evidence, but newer stuff might actually be better, but less tested]

I did a little quick searching for "knee stability training protocol" and.. found a few things that looked pretty obvious. Quads, hams, calves, etc. More or less what I'd expect. I don't suppose you have any secret sauce beyond that?

resistance training 2-3 times a week (the kind where you are in excruciating pain by the end, i.e. proper resistance training not aerobics masquerading as resistance training),

Ie, "train to failure"? If so, I was under the impression that training to failure is now considered less effective/useful.

(e.g. don't look for joint pain after trying a new style of movement, look for proxies in your blood).

I'm not an athlete, but what would the proxies be?

Comment by Randomized, Controlled (BossSleepy) on Is the length of the Covid-19 incubation period likely to be affected by whether you are vaccinated? · 2021-06-17T18:29:29.213Z · LW · GW

Thank you for the info dump.

Basically, my real theory is basically to follow my cravings, try to AVOID eating unless I CRAVE some food or drink (and eat half of how much I think I want, then get seconds after 10 minutes if I still wanna), use common sense (liberally sprinkled with evolutionary bullshit), copy the diets of people similar to me who seem successful, and cross my fingers.

This closely accords with my intuition, the only part I haven't been doing is the 10 min cool off for seconds. I'll add that.

Thank you. : )

Comment by Randomized, Controlled (BossSleepy) on The Apprentice Thread · 2021-06-17T18:14:44.287Z · LW · GW

[APPRENTICE] I'd like to learn more about investing and finance, to the extent that finance will help me understand investing. My goal in this is primarily being able to manage my own money/investments and ultimately to be able to reach financial independence so that I can work on effective/impactful causes and donate more. I've been reading more about cryptoassets lately, but don't have strong opinions yet about where is best to point my attention in this field.

[MENTOR] I'm a self-taught programmer who's done mostly web-programming (lot of Python, Django, some FE, some JS/node). I'm potentially available for some amount of mentoring in that area.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-16T19:00:33.665Z · LW · GW

This has good rather long and I'm out of time, but if you are interested - I could run through a diagnostic process for knee pain.

I haven't had a chance to digest this all, but I'd certainly be interested.

Comment by Randomized, Controlled (BossSleepy) on Is the length of the Covid-19 incubation period likely to be affected by whether you are vaccinated? · 2021-06-14T20:27:51.594Z · LW · GW

because even just 1 drink of alcohol wipes out a large percent of your immune cells for hours or days, and then your hematopoietic cells rebuild them at the cost of telomere shorting

Say waaaaaaaaaaaaaaaaaaa?

It's a bit unclear from your context: are you asserting this for everyone or primarily for people who are abusing alcohol?

I do have to say, I've always been pretty confused by the inconclusive evidence that drinking may have some positive health effects. Maybe I just tolerate alcohol less than average, but I've often felt like I was just dosing myself with poison based on one or two drinks and how bleeeech I would generally feel the next morning. There have been a number of times when I've felt like this might be a bad hedonic cost/benefit trade off, but there are a number of beers whose taste I like enough that I haven't really been tempted to just set a blanket no-booze policy.

In your judgement, is a blanket no-booze policy worth considering? (I'm a pretty infrequent drinker currently: a heavy drinking week might see three or four units; most weeks are zero units.)

Comment by Randomized, Controlled (BossSleepy) on Is the length of the Covid-19 incubation period likely to be affected by whether you are vaccinated? · 2021-06-14T20:20:43.552Z · LW · GW

No, this was great, I totally dug it and I'm just a random bystander.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-13T17:27:55.726Z · LW · GW

Can I clarify before I spend time writing a long answer - You are looking for a model that explains why you've now got pain in your foot (with a history of knee pain)?

Yup.

I'm also looking to better understand my PF pain.

Poor posture = Pain.

I'd say I'm somewhat confused about this model, based on a reasonable amount of reading. Paul Ingraham, Todd Hargrove and Greg Lehman all point at a lot of clinical evidence that postural and structual models of pain aren't very explanatory, which I think can be 80% pithy sumerized by "there are lots of cases where people have pain in tissues that appear healthy and no pain in tissues that show visible, gross lesions and other damage." I've been working a health coach for the past few months who seems smart and well meaning -- they recommended I make some (reasonably subtle) gait adjustments to help externally rotate the femur while walking. I was quite skeptical of this theory, but I've come across the cue before (ie, to try to emphasize the outer edge of the foot more than the inner), and I've been good-faith trying it to see what happens. I'm about 60% confident that this gait alteration may be involved in the ideopathic footpain -- I've had PF pain flairups before, but never ran into this foot tendon/ligament issue.

Thank you for the resources, I'll definitely spend time with those.

Comment by Randomized, Controlled (BossSleepy) on Cryonics signup guide #1: Overview · 2021-06-10T20:53:04.172Z · LW · GW

One of the obvious resurrection routes is via digitizing frozen brains. My intuitive sense is that we're more likely to get the imaging and virtualization tech before we get the detailed nano-tech that could repair all the cells.

and unless quantum physics change (and thereby the laws of the universe), the damage done with current cryo technology is too big to allow resurrection.

You have a QM based proof that cryonics can't work? I'm sure we'd all be very interested to see the details.

Comment by Randomized, Controlled (BossSleepy) on What are some important insights you would give to a younger version of yourself? · 2021-06-09T20:55:52.542Z · LW · GW

[Keep] cutting your expenses and read about financial independence. Stop running at [bad] proxies for the thing you're interested in, and figure out how to run at the thing you're interested in. There's a voice in the back of your head that will always find something to complain about in every situation. [I now believe this is what Buddhism means by "unsatisfyingness"]. Sometimes the secret will be to recognize that the voice is constant and adjust your expectations accordingly. Other people are not there to entertain you, or fulfill you.

I likely could have saved two or more romantic and personal relationships if I'd be more accepting of the last two points.

Comment by Randomized, Controlled (BossSleepy) on Dangerous optimisation includes variance minimisation · 2021-06-09T14:46:02.296Z · LW · GW

Why do we believe that we have variables that nobody cares about?

Nobody believes this, however we don't have a way to express all the things we care about in math or code yet.

Comment by Randomized, Controlled (BossSleepy) on Cryonics signup guide #1: Overview · 2021-06-08T22:25:54.872Z · LW · GW

The reddit post is about a year old, but pretty upsetting. It alleges a lot of incompetence around the transportation of patients who have recently died.

Poking around the r/cryonics for a few minutes I wasn't able to find any follow up. I'm eagerly following the issue.

Comment by Randomized, Controlled (BossSleepy) on We need a standard set of community advice for how to financially prepare for AGI · 2021-06-07T18:34:37.860Z · LW · GW

Probably both.

Comment by Randomized, Controlled (BossSleepy) on We need a standard set of community advice for how to financially prepare for AGI · 2021-06-07T17:01:19.253Z · LW · GW

I was listening to Buterin on the Tim Ferriss podcast this morning, he made an offhand comment that biotech is at a similar point that computers were in the 50s; that left it salient with I read this, but in conversation and from general reading I have a sense that there's a good chance that a lot of progress is about to be unlocked in the field due to machine learning, much cheaper / higher throughput genetic sequencing and DNA/RNA/protein synthesis and much better DNA editing techniques due to CRISPR.

Comment by Randomized, Controlled (BossSleepy) on We need a standard set of community advice for how to financially prepare for AGI · 2021-06-07T15:20:00.240Z · LW · GW

We should have a similar conversation [Question post?] for anticipating the consequences of transformative biotech.

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-07T15:00:43.166Z · LW · GW

It's similar to how Todd R. Hargrove is someone who gathered the knowledge he has primarily through feedback loops involves movement and is therefore more trustworthy when he says "I you do these movements, that happens" then when he speculates about what the involved neurons are doing.

Are you skeptical of the central nervous system sensitization pain mechanism?

Comment by Randomized, Controlled (BossSleepy) on What are good resources for gears models of joint health? · 2021-06-07T00:14:58.458Z · LW · GW

Fascia Research Congress. A few Rolfers like Robert Schleip and Thomas Myers

I'll look into the Fascia Research Congress and these two!

Tense fascia leads to high muscle tone and that can then make individual body parts tense enough to hurt. When the problem travels between different parts of the body that's often what's happening

Does that suggest that trigger-point release, various forms of massage and something like Paul Ingraham's mobalization prescription are good starting places?

From that point it frequently also happens that you get inflammation in that body part which produces additional issues.

Any suggestions how to tell if you have inflammation and what to do if you do? Ingraham's Patella Femoral Syndrome tutorial is basically a book disquisition about low-level systemic inflammation in the knee cap, and his prescription is: lots and lots of gentle rest. He suggests the knee cap may be an unusual joint in that it it's under a lot of pressure even if just sitting still with a knee bent at 90 degrees, so recovery can be hard, but I'm guessing "lots of rest + standard PRICE treatment" is the typical prescription for other inflamed joints?