Comment by Rijan on How to have Polygenically Screened Children · 2023-05-19T15:35:57.051Z · LW · GW

Hi, you suggested freezing embryos instead of eggs. However, a recent study found that frozen embryo babies are 2.5 times more likely to develop cancer. At the same time, a review article on IVF comes to the following conclusion (likely due to epigenetic factors):

IVF is associated with an increased health risk for the offspring in the form of malformations, functional dis- orders, and a poorer peripartum outcome. This is possibly caused by parental factors, but also by factors related to the IVF technology used. [...] Consequently, IVF should only be performed if a pregnancy cannot be achieved in another way.

This makes me want to consider two points: 

1. Assisted reproductive technology carries risks and couples that go through IVF should in any case do polygenic testing to offset these
2. Is the risk/benefit ratio worth it for couples that can conceive naturally, especially for something like merely 5 IQ points?