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This is quite reductionist and I admit this, but I'm guessing that "suffering" in itself is not something that anyone can quantify to know when there is "more" or "less". My guess is that one has to look every time for the physiological effects and by doing that, it is easier to answer when there is too much or there's room for more.
The same "stimulus" (e.g. grief -- probably one of the most common) will result in varied answers from the psyche and the physical, so I would say that a quantitative appreciation must start from the effects, and not the causes. And once effects are considered, any quasi-precise appreciation will end up in the physical.
Nevertheless, I would really enjoy to read more well advised answers, as it is a subject that interests me greatly.