How should I help us achieve immortality?

post by Hul-Gil · 2011-05-10T02:00:16.735Z · LW · GW · Legacy · 85 comments

Contents

85 comments

I was immensely glad to find this community, because while I knew intellectually that I was not the only person who felt that rationality was important, death was bad, and technology was our savior, I had never met anyone else who did. I thus determined my career without much input from anything except my own interests; which is not so bad, of course, but I have realized that I might benefit from advice from like-minded people.

Specifically, I would like to know what LessWrong thinks I should do in order to get into "immortality research." Edit: that means "what field should I go into if I want humanity to have extended lifespans as soon as possible?"

I feel immortality, or at least life-extension, is one of - if not the - most important thing(s) humanity can accomplish right now. I don't think I am suited to AI work, however. Another obvious option is an MD, but that's not in my temperament either. My major right now is biochemistry, in preparation for a doctorate in either biochemistry itself, or pharmacology.

I think there's a good chance that advances in this area could contribute to life extension; aging is a biochemical process, right? And certainly drugs will be involved in life extension. But is this the best place to apply my efforts? I have considered that biogerontology (http://en.wikipedia.org/wiki/Gerontology) might be better, as it is about aging specifically; but I don't know much about the field - only that Wikipedia says it is new and very few universities offer degrees in it. My final idea is nanotechnology of some kind; I believe nanomachines may be able to repair our bodies. I'm not sure what type of nanotechnology I'd be looking at for this, or if degrees in it are offered.

Any ideas, suggestions, or comments in general are welcome. I favor the biochemical approach as of now, but only through temperament. As far as I know, AI, biochemical/pharmacological methods, and nanotechnology are all about equally close to giving us immortality. If someone feels one option is better than the others, or has recommended reading on the subject, please share!

 

Thanks in advance, my new rational friends.

85 comments

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comment by Mitchell_Porter · 2011-05-10T02:12:38.770Z · LW(p) · GW(p)

I suggest you write to Athena Andreadis at Harvard, ask her what's missing from the SENS Foundation's "seven research themes", and try to fill the gap.

Replies from: Hul-Gil, Laoch
comment by Hul-Gil · 2011-05-10T02:39:54.052Z · LW(p) · GW(p)

Thank you! I will do so forthwith.

comment by Laoch · 2011-05-10T21:52:38.330Z · LW(p) · GW(p)

Maybe I need to more research on that lady, but I got the impression she thought the whole thing was bunk? Btw Hul-Gil I commend your zeal.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T03:10:52.556Z · LW(p) · GW(p)

Thank you. :D I hope to inspire everyone to feel the same way - then we'll be immortal in no time!

comment by Kaj_Sotala · 2011-05-10T07:15:27.911Z · LW(p) · GW(p)

Have you looked at the stuff SENS foundation is doing, and tried to figure out if any of it is close to what you're studying?

Their Academic Initiative especially seems aimed at people in your circumstances.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T03:11:09.685Z · LW(p) · GW(p)

Thank you - I am looking now.

comment by lsparrish · 2011-05-10T05:14:10.146Z · LW(p) · GW(p)

I recommend cryobiology research for consideration, if that's something that interests you. Achieving reversible cryopreservation (particularly of the brain) seems like a more modest near-term goal than developing a method of reversing aging.

Replies from: jsalvatier
comment by jsalvatier · 2011-05-10T21:52:33.342Z · LW(p) · GW(p)

Can you provide arguments/evidence for why it should be a relatively low cost goal?

Replies from: jhuffman
comment by jhuffman · 2011-05-11T20:08:17.687Z · LW(p) · GW(p)

Perhaps it presumes too much but it seems that many consider it possible we can preserve brain state information for an extended amount of time without understanding it or having any specific ideas of how to reconstitute a thinking being based on that information.

comment by MinibearRex · 2011-05-10T06:42:23.110Z · LW(p) · GW(p)

I'm in a similar situation (chemistry pre-med student). Personally, I'm interested in nanotech because that field is new, and requires researchers who are inventing the way forward. That appeals to me; I think it sounds fun, plus it's an important field for immortality. I don't have a lot of connections to that field though, although it's definitely something I'm looking into for graduate work.

Additionally, diseases like Alzheimer's are serious obstacles to immortality, and are really and truly horrible. Two of my grandparents are information-theoretically dead, even though they still have functioning hearts and lungs. They don't recognize me when I visit; they just think I'm another worker at the home they live at. That problem really needs to be resolved, or we will be stuck at lifespans of only a century maybe plus a bit more.

comment by James_Miller · 2011-05-10T02:12:21.044Z · LW(p) · GW(p)

The best way for you to advance research on immortality is to earn as high a salary as possible and donate money to people doing immortality research.

Replies from: ahartell, Desrtopa, Hul-Gil
comment by ahartell · 2011-05-10T02:55:05.378Z · LW(p) · GW(p)

I think this statement hold truer for individuals whose competitive advantage is best suited for a high salary career. It seems the OP is inclined towards science, so it makes sense to go into a scientific field, again one that plays to the individual's competitive advantage. I personally wouldn't know what to suggest, though. Porter's idea looks good, assuming there is a noticeable gap in SENS' research that they aren't actively trying to fill. As a Junior in High School, I've actually been thinking about this quite a bit, and I would also like to go into life extension or cryonics work.

comment by Desrtopa · 2011-05-10T02:17:27.488Z · LW(p) · GW(p)

Not everybody can follow this prescription though. Somebody has to do the actual research.

Replies from: James_Miller
comment by James_Miller · 2011-05-10T02:54:43.251Z · LW(p) · GW(p)

True but irrelevant to what Hul-Gil should do since his actions would have only a small impact on the total number of people who conduct immortality research.

Replies from: Desrtopa
comment by Desrtopa · 2011-05-10T04:56:30.501Z · LW(p) · GW(p)

Under what circumstances, then, would you say that it would be a good idea for someone interested in bringing about human immortality to go into research?

Replies from: nazgulnarsil
comment by nazgulnarsil · 2011-05-11T22:35:03.841Z · LW(p) · GW(p)

very high IQ and low social skills.

people with very high IQ and high social skills can generally make enough money to pay for several researchers.

comment by Hul-Gil · 2011-05-10T02:39:13.519Z · LW(p) · GW(p)

I'm asking specifically what field I should go into; perhaps that wasn't clear enough.

Your suggestion is not correct if my intellectual contributions would be more valuable than any or most monetary ones I could make. But don't think I have not considered the opposite, too; to that end, what's the best way to make money? Economists aren't as rich as I would have guessed.

Replies from: rwallace, James_Miller
comment by rwallace · 2011-05-10T12:51:56.105Z · LW(p) · GW(p)

If your passion is science, if at a gut level you believe that's where you can make the best contribution, do that. Making real money takes a hell of a lot of drive; it's not something that's at all likely to be accomplished by following the steps because you've been intellectually persuaded it's the course of highest utility.

The same is true in reverse, of course; if your passion is to start your own company, do that and donate money to immortality research.

In other words, don't try to choose in the abstract the career of highest utility. Choose from among those careers with high utility, that one where you have comparative advantage; and listen to your gut about where your comparative advantage lies.

Replies from: endoself
comment by endoself · 2011-05-11T21:20:05.789Z · LW(p) · GW(p)

Making real money takes a hell of a lot of drive; it's not something that's at all likely to be accomplished by following the steps

I think you're right, but many people here seem to disagree and it is quite likely I'm wrong; I haven't actually researched in detail how difficult it is do, say, financial trading. What evidence are you basing this on?

comment by James_Miller · 2011-05-10T02:53:18.528Z · LW(p) · GW(p)

The best ways to earn a high salary are to go into finance, law or to start your own business.

You should be careful to properly measure the marginal intellectual contribution you can make to a field. Think what would happen if the organization you would work for hired the next best candidate. Your marginal contribution is the difference between what you would do and what this second best candidate would do. You need to take into account that anyone who ends up paying you to conduct immortality research would likely have paid someone else to do it if you weren't around. In contrast, if you end up donating money to an organization that does immortality research then there isn't any other money this organization loses because they end up getting your funds.

Replies from: gjm, Hul-Gil, AlephNeil
comment by gjm · 2011-05-10T17:14:25.734Z · LW(p) · GW(p)

I think this account of marginal contribution is wrong. Here's a handwavy model to explain why.

Suppose there are N people in the world working on X, and you're the Mth best. And suppose (laughably) that every organization doing X hires exactly one person, the best person it can get. And (also laughably) that everyone works for the best organization they can, and that that's the one doing the most valuable work in X. Write A(n) for the importance of the nth-best organization's work and B(n) for the quality of the nth-best person's work.

OK. So the total utility we get is the sum of A(n) B(n). Now, suppose you weren't there. The organization employing you gets the next-best person instead, and then the next-best organization gets the next-next-best, etc. In other words, instead of A(1)B(1) + A(2)B(2) + ... + A(N)B(N) we get A(1)B(1) + ... + A(M-1)B(M-1) + A(M)B(M+1) + A(M+1)B(M+2) + etc. The total utility loss is therefore A(M)(B(M)-B(M+1)) + A(M+1)(B(M+1)-B(M+2)) + etc. The first term here is what James_Miller describes, but there are all the others too.

(Another way for the scenario to play out: Everyone's already employed; then you drop out and your employer has to hire ... whom? Not the next-best candidate, because s/he is already working for someone else. They'll get the (N+1)th-best candidate, not the (M+1)th-best. The most likely actual outcome is something intermediate between the one I described above and this one.)

Suppose, for instance, that the As and Bs obey a Zipf-like law: A(n) = 1/n, B(n) = 1/n. Then the utility loss is sum {M..N} of 1/n (1/n - 1/(n+1)) = sum {M..N} of 1/n^2(n+1) ~= 1/2 (1/M^2 - 1/N^2), whereas James_Miller's account gives about 1/M^3. If M is much smaller than N -- i.e., if you'd be one of the best in the field -- then James's figure for the utility loss is too small by a factor on the order of M. If M is comparable to N -- i.e., if you'd be towards the bottom of the pack -- then James's figure is too small by a factor on the order of N-M+1. In between, some slightly funny things happen. Other than right at the endpoints, it's a pretty good approximation to say that James's figure is too small by a factor of M(N-M)/N.

Replies from: endoself, gjm
comment by endoself · 2011-05-11T21:27:31.783Z · LW(p) · GW(p)

This applies well to small organizations or departments, but large organizations, especially universities, could hire researches to work in a field, rather than on a specific task. Researchers working on important problems can work on things that no one would do in their absence.

Replies from: gjm
comment by gjm · 2011-05-11T21:40:35.880Z · LW(p) · GW(p)

"X" was meant to be the name of a field rather than of a specific task. I don't think that makes much difference. But yes, there are contexts in which if you weren't available your work simply wouldn't be done. In that case, your marginal contribution equals your contribution, and once again, the "your contribution minus the next-best person's" calculation gives much too small an answer.

comment by gjm · 2011-05-10T20:28:43.645Z · LW(p) · GW(p)

A few other remarks.

If A(n)=1 (i.e., more attractive employers aren't actually doing more useful work) then the Miller marginal-utility loss is 1/M(M+1) and the gjm marginal utility loss is 1/M-1/N, for much the same ratio as before.

If A(n) or B(n) or both decrease really quickly with n -- A(n) = 2^-n, say -- then the error is smaller.

The super-naive approach of pretending that the marginal utility loss equals the utility your work would have done is a much better approximation than "replace self with next-best candidate and change nothing else" is.

comment by Hul-Gil · 2011-05-10T03:17:53.172Z · LW(p) · GW(p)

That's an excellent way to think about it. I had not considered it like that; it makes me feel less guilty about the possibility of going into finance!

However, intellectual contributions are not necessarily purchasable. That is, donating enough money for an organization to hire two mediocre scientists may not result in the insights of one slightly better scientist; margin size may not be linear. To paraphrase a quote from an article I've forgotten the rest of, "a hundred years of doggy living won't add up to one human insight."

Not to suggest I am so excellent as to make all other scientists look like dogs, of course. Rather, I feel that the insights of any one researcher are possibly unique. The example that comes to my mind is that of vulcanized rubber - discovered by accident. Who knows when it would have come about if Goodyear had gone into law instead? Who knows but that I might stumble on the Vulcanized Rubber of Immortality? In any case, a world where everyone researched immortality would be better than a world where one person researched it with the funds of everyone else.

Science is my true love and I don't think I shall abandon it, but finance is a little interesting. Do you suggest it just because financial careers come with high salaries, or do you think that understanding of finance means understanding how to manipulate money in order to become wealthy? I envisioned the latter for economics, but like I said, economists don't necessarily seem to be better investors than anyone else.

Replies from: None, jsalvatier
comment by [deleted] · 2011-05-10T05:42:05.992Z · LW(p) · GW(p)

To paraphrase a quote from an article I've forgotten the rest of, "a hundred years of doggy living won't add up to one human insight."

"Imagine running a dog mind at very high speed. Would a thousand years of doggy living add up to any human insight?" - Vernor Vinge on the Singularity

comment by jsalvatier · 2011-05-10T03:39:30.957Z · LW(p) · GW(p)

As for economists and investing, their standard advice is described in the comments here. The reason economists aren't fabulously wealthy is that financial markets are fairly efficient so it's hard to make money unless you have an edge.

Replies from: Vladimir_M
comment by Vladimir_M · 2011-05-10T04:53:29.758Z · LW(p) · GW(p)

The reason economists aren't fabulously wealthy is that financial markets are fairly efficient so it's hard to make money unless you have an edge.

One straightforward question to which I've never seen an answer is how the supposed existence of a science of macroeconomics can be reconciled with the efficient markets hypothesis, even the weak one. If you have come up with a macroeconomic theory that has non-trivial predictive power, surely it would be irrational to just publish it in a journal instead of first employing it to make some killer investments.

Replies from: jsalvatier, rhollerith_dot_com
comment by jsalvatier · 2011-05-10T15:23:41.787Z · LW(p) · GW(p)

Like Silas Barta, I have come to the view that a lot of macroeconomics is terribly confused. I have an ongoing mission to make sense of macroeconomics. My explanation of how most macroeconomic theories of macroeconomic fluctuations work at their core is here.

I'm not sure I understand your question, so if I'm answering past you, let me know. Anyway, if you came up with a model that predicted macroeconomic variables better than the marginal traders who trade assets strongly affected assets, yes you could make a killing. As I see it macroeconomic modeling is about producing theoretical understanding rather than producing predictions about the path. If we had really good and detailed prediction markets of all important macroeconomic measures, that would generate good predictions but it might not be very enlightening about what policy makers should do differently and why. In other words, modeling answers questions about what forces are at work while prediction about whats going to happen at some specific point in time is about what the net effect of those forces are.

Theoretical macroeconomics can help us understand what kinds of things we should try to measure, what kinds of general rules policy makers should adopt etc. A good predictive mechanism can help us determine what people should do right now (should your grocer expect an increase or decrease in sales), whether policy makers do a good job.

Does that clarify things?

Replies from: Vladimir_M
comment by Vladimir_M · 2011-05-10T18:07:47.034Z · LW(p) · GW(p)

Anyway, if you came up with a model that predicted macroeconomic variables better than the marginal traders who trade assets strongly affected assets, yes you could make a killing. As I see it macroeconomic modeling is about producing theoretical understanding rather than producing predictions about the path.

Such "theoretical understanding" is as if you had a theory of physics that purported to "explain" past observations but was unable to make any predictions about future events. That is not science. At best it's just empty philosophizing, and at worst pernicious bullshit used to rationalize actions out of touch with reality.

As for the relevant prediction markets, they already exist for all practical purposes. I don't know much about finance or investment, but I do have at least a rough idea how any correct non-trivial macroeconomic prediction could be translated into a winner investment strategy.

Replies from: jsalvatier
comment by jsalvatier · 2011-05-10T19:27:31.537Z · LW(p) · GW(p)

Perhaps I wasn't clear. I don't think that macroeconomic theorizing is useful even if it predicts nothing. Obviously that's useless. I think that macroeconomic theorizing is useful even if they don't generally outperform market predictions of market forcasted variables because it gives you different kinds of information about the economy.

For example, imagine a world where relevant traders have very good models for predicting the value of the S&P500. However, these models are proprietary, detailed and heavily specialized for predicting the S&P500. Academic models are open, relatively simple and based on 'first principles'.

In this scenario, how useful are these two types models? Depends on what kind of question you're asking:

  • What will the value of the S&P be in 1 year? Trader models useful. Academic models useless.
  • What kinds of alternative monetary institutions would be better than current ones? Trader models useless. Academic models useful.

Perhaps you could formulate prediction markets to answer the second kind of question well, but I sure don't know how and in any case is not currently something people do.

There are also plenty of non-trivial macroeconomic predictions that you cannot make money off of. For example, 'employment will be 1 point higher in 1 year' is non-trivial, but it could be information already perfectly incorporated into the markets. 'printing money now increases employment and inflation for 1 year out' is also nontrivial but may also be fully accounted for. If you don't have access to markets that predict precisely this information, such forecasts can easily be useful.

Also, all relevant prediction markets do not exist. Examples: there are no very liquid unemployment prediction markets, there are no very liquid real GDP prediction markets etc. What is individually useful to trade is not necessarily the same thing as what is socially valuable to know.

Replies from: Vladimir_M
comment by Vladimir_M · 2011-05-10T20:22:39.714Z · LW(p) · GW(p)

What kinds of alternative monetary institutions would be better than current ones? Trader models useless. Academic models useful.

It may well be that the existing trader models are useless for answering this question, but any novel model that is capable of answering them should ipso facto be able to provide useful investment information. There are endless public controversies over the expected effects of the current monetary policy, which have direct bearing on all sorts of markets, and if you can forecast their effects with more accuracy than any existing model, you should be able to beat the markets.

There are also plenty of non-trivial macroeconomic predictions that you cannot make money off of. For example, 'employment will be 1 point higher in 1 year' is non-trivial, but it could be information already perfectly incorporated into the markets.

If you really know that employment will be one point higher in a year, there are straightforward implications on trading. For example, people who bet (possibly as a way of hedging their investments) that there's going to be a very bad recession within a year are certainly wrong, and you can profit by betting against them. If I, a complete amateur, can easily think of such strategies, then I can only imagine what expert financiers could do with this information! It's similar with predicting NGDP and all other aggregate variables.

I don't see any logical possibility how some macroeconomic prediction could be at the same time: (1) meaningful and non-trivial, (2) more accurate than the state of the art, and (3) useless for investment.

Replies from: jsalvatier
comment by jsalvatier · 2011-05-10T21:04:19.983Z · LW(p) · GW(p)

Replying by paragraph:

3) sure; my point was that (1) does not imply (2).

1) I'm not clear on how you're disagreeing with me, so this is mostly going to be a reworking of my previous answer. Let me know if you can clarify your disagreement.

Academic and trader models can be better at answering different questions. Neither one need always dominate the other. Academic models might be better at answering questions which rarely come up, for example 'what happens when we change monetary institutions?', so not offer useful investment advice except in those rare occasions but still be useful for deciding what options policy makers should consider.

Academic models can also provide much more understandable and accessible models of the economy (see 2). Non-traders may find these much more useful than trader models (which they may not have access to or be able to understand).

2) No. Remember I stated that this information was already taken into account by the market. NGDP, employment etc. are not random walks (Edit: I mean they are not martingales); their expected future value is not independent of past values. Unemployment is highly non random see here. Some macroeconomic variables are random walks, for example stock market indexes, but most of them are not.

Replies from: Vladimir_M
comment by Vladimir_M · 2011-05-11T20:30:19.709Z · LW(p) · GW(p)

I'm not sure I understand you either. Are you actually saying that if I had an oracle capable of telling me what, say, the rate of unemployment or NGDP growth will be in a year, it would not be possible to make investments with above-market returns using this information?

Moreover, I am at a loss trying to imagine a theory that would enable us to predict with reliable accuracy what would happen if we changed the monetary institutions in a given way, and which wouldn't also enable us to get reliably accurate information on the uncertain and controversial questions about the consequences of the present monetary policies. This would also constitute valuable investment information. (Or do you think it wouldn't?)

On the whole, the problem is that I simply cannot imagine any questions that macroeconomic theories purport to handle where a truly reliable and non-trivial information would not be valuable for investment.

Also, you can't answer these questions by claiming that the relevant information has already been incorporated into the market prices, only in some obscure way that we now seek to disentangle. Many investments are specifically made in order to hedge against uncertainty in macroeconomic trends. If you have a theory that eliminates these uncertainties, or at least provides more accurate probability distributions, there's a straightforward killing to be made there.

Replies from: nazgulnarsil, jsalvatier
comment by nazgulnarsil · 2011-05-11T22:41:24.606Z · LW(p) · GW(p)

"On the whole, the problem is that I simply cannot imagine any questions that macroeconomic theories purport to handle where a truly reliable and non-trivial information would not be valuable for investment."

One where the prediction is longer than your investment window.

comment by jsalvatier · 2011-05-11T21:42:31.327Z · LW(p) · GW(p)

1) It all depends on whether your predictions are better than or worse than the relevant traders. If the traders already have access to such an oracle, you won't be able to make any money; if they don't, you will. Many macroeconomic variables of interest (GDP, employment etc.) are not martingales which means that predicting their movements is not the same thing as predicting them better than relevant traders. Being able to predict an asset price difference (between now and some future time) and acting on that information tends to move the price to eliminate that difference now. Being able to predict say a difference in unemployment (between now and some future time) does not necessarily tend to move unemployment to eliminate that difference right now.

Perhaps the following is a more relevant example: lets that you and everyone else found out a couple of days ago that aliens are going to land on earth in a month. The variable aliens-on-earth (binary) is certainly an important macro variable. Naturally market prices currently reflect the fact that aliens will soon be among us. The current value of aliens-on-earth, however, is False and no amount of trading can change that. Aliens-on-earth is not a martingale; its current value is not equal to its discounted expected value and you can predict it quite well (aliens-on-earth(t) = {False for t < 1month and True for t >= 1 month).

2) I'll give a concrete but extreme question: what would happen if the US moved to a uranium based commodity money system? Would it be good? bad? Trader based models are likely pretty useless for this because no one thinks this is likely to happen so there are few benefits to developing a model for it. Even if they did, you might not have a way to get at those predictions. However, you could get a rough idea about the consequences by building an economic model for this scenario taking into account the economics of money, estimates about the stock and potential supply of uranium, the costs of avoiding radiation poisoning during transactions etc.

Obviously this question is extreme, but questions like it are valuable: should we move to a competitive currency system (free banking)? what would that look like? How does an optimal central bank behave (for various definitions of optimal)? Are countercyclical unemployment insurance extensions welfare improving? Is countercyclical government spending welfare improving?

I have some opinions on the preceding questions including that some of them are obviously of little interest, but I only came to them because I learned some macroeconomics.

4) 'There's potential money to be made by selling rough macro models to say industrial producers' is a fair point. However, it's a lot of work to turn a model that says 'keeping money supply constant, an increase in people's desire to hold money produces recessions' to something that might be useful to producers for planning. It's the job of macroeconomists to come up with the former not the latter in the same way that it's the job of government funded battery researcher to come up with basic theory related to batteries, or a computer scientist to come up with interesting and potentially useful classes of algorithms. If one of these researchers comes up with something really big that is immediately implementable, perhaps they will go off and start a company to take advantage of the idea, but generally they stick to basic theoretical research because thats whats easy and comfortable and where their advantage is.

Replies from: Vladimir_M
comment by Vladimir_M · 2011-05-12T01:20:45.330Z · LW(p) · GW(p)

(1) I know what martingale variables are, but I don't see why the non-martingale nature of the macroeconomic variables is relevant. Clearly, if you have figured out a novel way to predict the coming of the aliens ahead of others (or even just to predict its timing and other details more accurately), you can get rich by figuring out how their coming will affect the markets. This is perfectly analogous to a theory that will predict various macroeconomic variables more accurately than the state of the art, since these variables have predictable effect on asset prices. (In fact, once you have this information, they are no longer martingales for you, since e.g. if you know a recession is coming withing a year, the expected trend for countercyclical assets is upward.)

Or to put it differently, from all that you have written thus far, I still don't see a concrete example (either actual or hypothetical) of the thing whose existence you assume: macroeconomic predictions that are interesting, novel, accurate, and at the same time useless for beating the markets.

(2) I understand that there are hypothetical questions about monetary systems where an accurate answer would have no practical implications by itself. However, presently we are in a situation where there are deep and bitter disagreements even about the predicted consequences of the ordinary and standard monetary policy options. What I find implausible is that one could obtain correct answers of the former sort without a theory that would at the same time be able to give more accurate answers to questions of the latter sort (which would again translate into investment information in a straightforward way). It would be as if you had a theory of mechanics capable of predicting the motions of hypothetical planetary systems but of no use for practical technical problems.

(3) Regarding your point about theoretical vs. applied research in other areas, the same heuristic actually is widely applicable. Whenever you see people doing research into something that should have straightforward practical applications, but you don't see them running to monetize the results, something fishy is likely going on.

Of course, sometimes there is real insight that can't be monetized in any obvious way, like for example fundamental theoretical physics. However, there is an essential difference here. A physical theory can make predictions only about things that are of no business interest, so in fact you have to spend money to contrive experimental setups to test it. In contrast, anything that a macroeconomic theory might be making predictions about and that might actually occur in the real world is inherently of business interest. (And again, if you have a counterexample, I'd be curious to hear it.)

Replies from: jsalvatier
comment by jsalvatier · 2011-09-01T20:13:03.822Z · LW(p) · GW(p)

For some reason I feel compelled to return to this topic:

My point is not that macroeconomics is a great field filled with great insights (it's not and most macro theorists are terribly confused) but that it's not as ridiculous as you seem to imagine it that some economists have novel, interesting and true things to say about inflation, unemployment, GDP etc and are not themselves fabulously wealthy.

(1) For example, some macroeconomic theories predict behaviors like the parable of the babysitting co-op. You can also run experimental economies (like this) and make predictions about the behavior of the economy.

I might set up a play economy where different people produce different goods and trade and consume them. Money is traded but not produced. We let this economy do its thing for a while and then suddenly (and without announcing in advance) give everyone 20% more money. Using my favorite macro theory I could make a number of interesting and novel predictions about what will happen (after a long time, prices will be 20% higher; in the short run people will devote more resources to producing traded goods instead of traded goods). Because this is basically irrelevant to the workings of the real economy, my predictions will be both more accurate than market predictions as well as useless for making money in financial markets.

Such theories would also make predictions about how good of an idea it would be to transition to a different monetary regime (say a competitive currency regime).

(2) As I said before, if traders approximate the parts of your model that are directly applicable then you don't have any useful information advantage.

(3) Sure, and there's plenty to be skeptical of in mainstream macro, but that doesn't imply unlimited skepticism.

comment by RHollerith (rhollerith_dot_com) · 2011-05-10T06:24:50.475Z · LW(p) · GW(p)

Yeah, well, the way macroeconomists in the U.S. seem to make killing is by becoming advisors to the government, then giving advice that enriches them or their friends.

comment by AlephNeil · 2011-05-10T05:52:02.626Z · LW(p) · GW(p)

someone else to do it if you weren't around.

But how much money would that "someone else" otherwise have donated to immortality research, if they hadn't got the research job themselves?

comment by Vladimir_Nesov · 2011-05-10T09:16:45.466Z · LW(p) · GW(p)

and technology was our savior

Easy there. Risk from technology constitutes the greatest long-term problem we have right now. It's not at all clear that the benefits outweigh this problem.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T03:12:41.096Z · LW(p) · GW(p)

I do tend to get pretty enthusiastic about technology. It might end up destroying us before a natural disaster would, but at least we have the theoretical chance to build a much better world for ourselves - a chance we wouldn't ever have without it, I think.

Replies from: Vladimir_Nesov
comment by Vladimir_Nesov · 2011-05-11T08:58:31.629Z · LW(p) · GW(p)

False dichotomy. If a flood is about to destroy your village, total absence of water that would make everyone die of thirst is not the only alternative, and imagining this alternative shouldn't make you "enthusiastic about water" when there's that flood to divert. Don't think about technology as a package deal, that obscures the specifics.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T21:34:20.722Z · LW(p) · GW(p)

Okay, I see what you meant by your original reply. My reply was based on the idea that you meant a total absence of technology might be preferable. If that seems like a ridiculous idea to you, well, it does to me too - and I'm confused and disgusted by the fact that I have spent a lot of time arguing against people who think that very thing: technology bad... all of it.

Replies from: Vladimir_Nesov
comment by Vladimir_Nesov · 2011-05-11T21:47:28.190Z · LW(p) · GW(p)

This is a common enough failure mode: as soon as "sides" are identified, only arguments in favor of your own side will get any regard. But in reality, there are always positive and negative aspects for any situation or policy, even where the better decision is absolutely clear. Policy Debates Should Not Appear One-Sided.

comment by lucidfox · 2011-05-10T17:09:45.725Z · LW(p) · GW(p)

The question to ask before the question in the header is, "Should you?"

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T03:17:06.864Z · LW(p) · GW(p)

Obviously, I have already asked this. Since I have stated life extension is going to be my life's work, I probably concluded that yes I should. (And with pretty hefty "surety and importance coefficients"!)

So do you actually mean "I don't think life extension/immortality is a good idea"?

Replies from: lucidfox
comment by lucidfox · 2011-05-14T17:21:02.016Z · LW(p) · GW(p)

Yes, that's what I mean.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-14T21:08:49.918Z · LW(p) · GW(p)

Why not?

I think it's a good idea for a few reasons. Mainly, that death is bad in the abstract, since there is no afterlife and it is the end of experience and thus happiness; and bad for me personally, since I don't think there is an afterlife and I want to continue to experience happiness. There is also the associated grief from those who loved the departed, and the decrepitude of age that makes life not worth living for some.

The only aspect of immortality I don't like is the population problem, and I have no reply for that; but I'm mainly concerned with those who oppose it on ideological grounds - like those who might say "death gives meaning to life". To which I say: what meaning? Are your experiences enhanced by the looming prospect of you and everyone you love ceasing to exist forever - or does this provide sadness and anxiety? For almost everyone, it is the latter. My life would seem even more* worthwhile if I did not have a mere ~76 years.

*(Even if you are religious, there is a chance you are wrong, so this is still a distinct possibility.)

To use an example of Eliezer's, if the benefit of death is so much greater than that of immortality, would an immortal want to die? Probably not, unless they were tired of life. And that, I can understand; when I say immortality, I really mean the ability to choose when you die. I object not to dying when one wishes to, if one ever does, but to the dying being forced upon us, with no concern for our desires. So the question becomes, would an immortal want to be subject to an arbitrary death date? I cannot imagine this ever being the case.

Of course, if you are a theist, then this argument would become about the afterlife. I would certainly question a God who sets up a system like this universe, but that's a different debate.

Replies from: Desrtopa
comment by Desrtopa · 2011-05-15T00:58:41.059Z · LW(p) · GW(p)

The only aspect of immortality I don't like is the population problem, and I have no reply for that

I used to worry a lot about overpopulation, but not so much anymore. We don't have an overpopulation problem, we have a resource overconsumption problem. This is most likely easier to engineer around than death is; it's not like we haven't jacked up the human carrying capacity of the earth several times already.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-15T09:29:37.195Z · LW(p) · GW(p)

That's true. Thanks for pointing it out! The U.S.A, for instance, is still mostly empty space, and that goes even for Europe, I think.

comment by Curiouskid · 2011-11-26T19:17:02.777Z · LW(p) · GW(p)

I was under the impression that even if SENS research is successful, it won't be immortality that we achieve, but "only" much longer life spans. True immortality wouldn't be possible without WBE.

Replies from: lessdazed, daenerys
comment by lessdazed · 2011-11-26T20:16:34.073Z · LW(p) · GW(p)

True immortality

In a misunderstanding revolving around a word, replace the word with others instead of modifying it with "true".

Replies from: Curiouskid, wedrifid
comment by Curiouskid · 2011-11-26T20:22:26.140Z · LW(p) · GW(p)

Living for 1000+ (WBE) years as opposed to 200 (SENS).

Replies from: lessdazed
comment by lessdazed · 2011-11-26T20:32:44.757Z · LW(p) · GW(p)

WBE earth years, yes? Not subjective ones?

comment by wedrifid · 2011-11-26T22:06:13.814Z · LW(p) · GW(p)

Given that immortality is a word with a reasonably clear definition using a modifier like 'literal' or 'actual' (but, as you say, definitely not 'true') would be sufficient. Especially when the 'other words' are in the previous sentence.

Incidentally... the claim seems just wrong. You don't need WBE to achieve immortality. Although at the level of technology required to achieve something sufficiently reliable as to be called immortality without WBE the WBE tech would probably be comparatively trivial.

comment by daenerys · 2011-11-26T19:34:12.947Z · LW(p) · GW(p)

I was under the impression that even if SENS research is successful, it won't be immortality that we achieve, but "only" much longer life spans. True immortality wouldn't be possible without WBE.

"True" immortality isn't possible at all, because eventually the universe will end.

Replies from: Curiouskid
comment by Curiouskid · 2011-11-26T21:20:43.633Z · LW(p) · GW(p)

I haven't read a whole bunch on cosmology, but I don't think that that is entirely certain. Especially if we have a super-intelligence that is trying to make sure that the universe doesn't end. Also, the difference between 200 years and 2^200 years enormous.

Replies from: wedrifid
comment by wedrifid · 2011-11-26T22:22:49.769Z · LW(p) · GW(p)

Also, the difference between 200 years and 2^200 years enormous.

Yet when cast to a boolean is 'true' and when negated to equality instead of difference is 'false'. I suppose that kind of difference matters to people who, say, really don't want to ever die. The difference takes on a whole new meaning when it is the difference between (infinity - 200) and (infinity - 2^200)

Especially if we have a super-intelligence that is trying to make sure that the universe doesn't end.

The space of credible cosmologies where the will of even a super-intelligence from within the system being able to have an impact on that one way or the other seems comparatively small, does it not?

I haven't read a whole bunch on cosmology, but I don't think that that is entirely certain.

This seems to be your main objection and I think you're spot on.

comment by DanielLC · 2011-05-10T02:27:39.024Z · LW(p) · GW(p)

Personally, I think immortality is overrated, at least by people who realize it's important at all.

You're not inherently more valuable than anyone else. Ergo, preventing your death would be no more valuable than replacing you afterwards. In addition, if we could replace you with a happier entity, it would be an improvement.

That said, replacing people is expensive. Immortality is still incredibly valuable for that reason.

Replies from: fubarobfusco, Hul-Gil, Kaj_Sotala, Automaton
comment by fubarobfusco · 2011-05-10T04:17:41.154Z · LW(p) · GW(p)

Ergo, preventing your death would be no more valuable than replacing you afterwards.

Well, here's the thing. My values and abilities today have taken 32 years to develop. I can identify several distinct stages where I was undergoing rapid change, and several where I was undergoing slower change; but nonetheless, replacing me today with an arbitrary newborn baby, a 2-year-old, 4-year-old, 8-year-old, or 16-year-old would not seem to be a one-for-one trade.

I certainly think the world would be worse off if my current 32-year-old self were replaced with my 16-year-old self. I was a bit of an asshole at 16.

(Sadly, I don't know of any way to demonstrate improvement that doesn't amount to either wealth signaling, wisdom signaling, or drama.)

I wouldn't assert that the value of a human life necessarily rises with age — equating experience with value. First, some people do squander their potential; and some people do start with more potential than others. But worse is age-related decline. The fact that people whose lives, experience, and wisdom I value are succumbing to the failure of their evolved physiological substrate is a dreadful thing. It's hard for me to read a Terry Pratchett novel today, knowing that his brain is right now literally falling apart due to Alzheimer's disease.

The average 72-year-old has less to offer the world than the average 24-year-old — precisely because of age-related decline. And that's a horrifying, disgusting fact. Preventing biological death without preventing mental decline is not a valuable outcome to me; I want people to retain their personality, their wit, their knowledge, and not just their metabolic function.

I don't think this is any kind of uncommon view around here — but longevity with intact mental function is an obvious win for preserving the value represented by human cognition.

Replies from: AlephNeil
comment by AlephNeil · 2011-05-10T06:13:52.845Z · LW(p) · GW(p)

Good answer, but I think DanielLC probably intended to cover it with his final line "replacing people is expensive. Immortality is still incredibly valuable for that reason".

At the moment, people have to squander effort [which could otherwise be spent playing video games] on finding food to keep their muscles working and their bodies at the right temperature. They also have to squander effort on feeding and educating youngsters and looking after the elderly. Curing aging will largely dispose of the second kind of wastage, which is a big win.

But I still think DanielLC is right - people do overrate immortality, believing that there's something terribly important about their own survival into the far future, simply because it is their own, going way beyond any objective assessment of their value and importance in the world.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-10T06:34:46.851Z · LW(p) · GW(p)

Rethink that last paragraph.

1.) An objective assessment says nothing of their value and importance in the world, because value and importance are assigned by individuals for themselves.

2.) To say wanting immortality is overrating the importance of your own life is like saying that liking the color green is overrating the importance of your own artistic ability - totally nonsensical.

3.) Technological immortality is not just for oneself; I think it is probably rated so highly important because it is for everyone. Everyone must die, and any death is as tragic as any other: to think one must only care about immortality for one's own sake is fairly cynical.

4.) Finally, immortality is almost guaranteed to be more important than any other goal one could have. Anything else can be deferred and accomplished once you are immortal, but once you have died, that's it.

You should give this article a read-through, I think:

http://lesswrong.com/lw/1yi/the_scourge_of_perversemindedness/

Insisting upon calling your own life unimportant is not rational, but perverse.

Replies from: nazgulnarsil, DanielLC
comment by nazgulnarsil · 2011-05-11T22:44:54.629Z · LW(p) · GW(p)

"Insisting upon calling your own life unimportant is not rational, but perverse."

I think it's a signaling function. leaders almost universally seem to push this sort of line forward.

comment by DanielLC · 2011-05-10T16:27:07.852Z · LW(p) · GW(p)

1.) An objective assessment says nothing of their value and importance in the world, because value and importance are assigned by individuals for themselves.

From what I can gather, most everyone here is consequentialist, but some are egoist, and some are utilitarian. I'm a utilitarian. I think happiness is inherently valuable. I don't really know how I can argue about it, and if I did, I'd make it a top-level post, but it's good to at least find out exactly where we disagree.

2 is basically restating 1

3.) Technological immortality is not just for oneself; I think it is probably rated so highly important because it is for everyone. Everyone must die, and any death is as tragic as any other: to think one must only care about immortality for one's own sake is fairly cynical.

I meant that immortality for anyone is over-rated. Death isn't in itself tragic. It's that once you die, you are no longer living, and thus no longer happy. If you replace the person who died with someone else, there's still life, and there's still happiness. The first person isn't living anymore, but the second wouldn't be living otherwise.

4.) Finally, immortality is almost guaranteed to be more important than any other goal one could have. Anything else can be deferred and accomplished once you are immortal, but once you have died, that's it.

Is there any reason to believe that the next generation will be less rational than this one? In any case, this isn't something inherently bad about death.

Insisting upon calling your own life unimportant is not rational, but perverse.

I consider my life very important. I just don't consider it uniquely important. If you replace me with someone who's life is equally important, there's no net gain or loss.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-11T02:36:36.591Z · LW(p) · GW(p)

I'm a utilitarian too; I posted arguments #1 and #2 because I don't know how I could argue for inherent value either, and Aleph might not be utilitarian. Note, though, that happiness can be inherently valuable, yet the same event can still result in different utility (or importance) for different people: Aleph may not value his own life as much as I value mine, causing immortality to make me more happy than it would make him.

I think you are arguing against straw men, however. No one has said, as far as I'm aware, that one's own life is necessarily uniquely important, nor was this implied. I have not seen anyone suggest that lives aren't equivalent in importance, and neither is this required for immortality to be valuable. And what does the next generation's rationality have to do with the fact that death prevents one from maximizing one's own happiness? As my happiness is inherently valuable, it's inherently valuable to me to maximize my own happiness, whether or not the next generation is happy. Surely it is better for our happiness to be added than for theirs to replace my own.

Even by your own examples, immortality is important. You make the argument that happiness would be the same if a death was mitigated by a new life - and this is true, but as an example, it is flawed: how often does that happen? In real life, death does not usually result in new life, so utility is increased dramatically by defeating death. But even if we assume that every death is balanced by a new life, total utility would be most increased if there was new life without the corresponding death.

It seems like you put aside all the drawbacks to death advanced so far - the sadness of others; the debility of age; the fact that we already know how to create new life, thus making death the main enemy of utility; the cost of replacement people; lack of happiness once dead - and wave it aside, saying "besides all those, death isn't so bad." Well yes - death isn't so bad, without all the bad things about death!

I'm not sure exactly what you're trying to say here. Your original statement was meant to point out that immorality is "not as important as people think", right? Who is it that thinks immortality is overrated, then? Apparently not me, since we don't appear to actually disagree that death is bad and immortality is good - which is all I've claimed. (We do disagree below, about death not being the end of the world, but that's not any claim I've made before.)

comment by Hul-Gil · 2011-05-10T02:45:21.572Z · LW(p) · GW(p)

Preventing my death would be no more valuable to who? A happier entity would be an improvement for who? Certainly not for me. Preventing the death of an already-conscious being would be more valuable to said being; probably to most other people, too - is it okay to murder someone if you're going to have a baby to replace them?

We already have a method for making new people, so preventing the deaths of those already here has higher priority, I think.

Replies from: DanielLC
comment by DanielLC · 2011-05-10T16:28:49.907Z · LW(p) · GW(p)

Preventing my death would be no more valuable to who?

Preventing your death would be exactly as valuable to you as replacing you would be to the guy who replaces you.

I don't really know any good way to argue against egoism.

comment by Kaj_Sotala · 2011-05-10T07:07:48.944Z · LW(p) · GW(p)

Look at all the ailments old age brings with it, from physical frailness to dementia, and the fact that people may have to spend decades in nursery homes when they'd rather be living independent lives.

I spent a year working at a service home. This was a private institution with motivated staff, a good staff-to-customer ratio and customers who were all relatively physically fit. Yet few of them really seemed happy with their circumstances. I'm pretty sure they would all have preferred to be in a better shape.

According to The Happiness Hypothesis, the five external circumstances affecting your happiness are noise, commuting, lack of control, shame and relationships. A declining physical condition reduces your control and may cause you to experience feelings of shame due to your helplessness. It also erodes your relationships as the people you know die and it gets harder to go meet the living ones, and you have less energy to make new friends.

Age-related decline is one of the biggest humanitarian catastrophes in our age.

Replies from: knb, DanielLC
comment by knb · 2011-05-10T07:37:01.119Z · LW(p) · GW(p)

According to , the five external circumstances affecting your happiness are noise, commuting, lack of control, shame and relationships.

What goes before the comma?

Replies from: Kaj_Sotala
comment by Kaj_Sotala · 2011-05-10T08:52:40.376Z · LW(p) · GW(p)

Fixed, thanks.

comment by DanielLC · 2011-05-10T16:32:14.275Z · LW(p) · GW(p)

That's what I meant about it being expensive.

Perhaps I should rephrase it. It's quite likely that death cuts our total productivity in half, if not worse. Its cost dwarfs that of every government put together. It's just not the end of the world.

Replies from: ArisKatsaris
comment by ArisKatsaris · 2011-05-11T14:48:05.966Z · LW(p) · GW(p)

It's just not the end of the world.

Forgive me for saying the obvious, but death has indeed been the subjective end of the world for everyone not currently alive. If someone wants to save the world for the sake of its people (not just for its own sake), then it is needed that they don't die.

comment by Automaton · 2011-05-10T02:57:50.698Z · LW(p) · GW(p)

I agree that if we're only considering the person who dies and the replacement person, that preventing someone's death and creating another person are pretty much the same, but I think the pain caused to others by someone dying is usually outweighs the happiness caused by bringing another person into existence. In any case, the costs of death to the people who are still alive need to be taken into account.

Replies from: DanielLC
comment by DanielLC · 2011-05-10T16:33:49.421Z · LW(p) · GW(p)

While there is sadness associated with death, that cost is dwarfed by the expense of raising and training replacements, and people getting less effective as they age.

My point wasn't that death doesn't matter. It's just not the end of the world.

Replies from: Hul-Gil, ArisKatsaris
comment by Hul-Gil · 2011-05-11T21:46:00.672Z · LW(p) · GW(p)

Well, as far as you know, it is the end of the world. Solipsism is a rationally defensible position, though I personally feel it's only worth keeping in mind to remind one of the limits of knowledge, and is not a philosophy that should actually govern behavior. (Thus this is intended as a comment only, not a refutation).

Replies from: thomblake, Vladimir_Nesov, DanielLC, Larks
comment by thomblake · 2011-05-11T22:18:13.091Z · LW(p) · GW(p)

Solipsism is a rationally defensible position

This reminds me of a story Bertrand Russell liked to tell: (Quoting from Wikipedia allegedly from Human Knowledge: Its Scope and Limits)

I once received a letter from an eminent logician, Mrs. Christine Ladd-Franklin, saying that she was a solipsist, and was surprised that there were no others. Coming from a logician and a solipsist, her surprise surprised me.

comment by Vladimir_Nesov · 2011-05-11T22:50:27.342Z · LW(p) · GW(p)

Solipsism is a rationally defensible position

Nope. You'd have to post an output of your reasoning to give us an opportunity to find a bug. Other than that, I can only direct you to the metaethics and zombie) sequences.

Also, using the word "rationally" here is a bad idea, since it doesn't add anything other than misleading connotational gloss. (A position defensible "rationally" as opposed to defensible in what manner?)

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-12T01:59:22.006Z · LW(p) · GW(p)

Suggestion noted. I posted it because I felt that it was tasty connotational gloss, but accuracy is more important than "taste".

"Nope. You'd have to post an output of your reasoning to give us an opportunity to find a bug."

Are you saying you disagree with my statement, or that positions can only be claimed to be defensible if reasoning is provided?

Replies from: Vladimir_Nesov
comment by Vladimir_Nesov · 2011-05-12T10:10:11.594Z · LW(p) · GW(p)

Are you saying you disagree with my statement, or that positions can only be claimed to be defensible if reasoning is provided?

I'm saying that your statement is wrong, but I can only convince you of that if you give more information about why you believe it, and what exactly it is that you believe.

comment by DanielLC · 2011-05-11T23:03:41.781Z · LW(p) · GW(p)

How rationally defensible? If you're 99% sure, you'd effectively value everyone else at 1% what you value yourself. This would still be enough to make you dedicate your life to charity, for example.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-12T01:55:41.524Z · LW(p) · GW(p)

Agreed. That's why I think it's incorrect to use solipsism as a basis to decide ethics.

comment by Larks · 2011-05-11T22:59:03.626Z · LW(p) · GW(p)

a rationally defensible position

Rationality is about finding the unique set of things to believe, and how strongly to do so. It's not about defending ideas; that sounds like defending the bottom line.

Replies from: Hul-Gil
comment by Hul-Gil · 2011-05-12T01:52:39.242Z · LW(p) · GW(p)

I didn't suggest it was about defending ideas. I only suggested that a particular idea could be defended by rationality. I don't think that implies the sole use of rationality is to defend ideas.

comment by ArisKatsaris · 2011-05-11T14:50:59.074Z · LW(p) · GW(p)

It's just not the end of the world.

Yeah it is. The end of the world for the person that's dying.