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Without relying on mass media, i've seen far too many simulations and demonstrations (various camera and imaging types) and far too many detailed articles specifying particle size, mechanisms of viral distribution, viral load and the like to convince me that there is sufficient efficacy to warrant their use.
Yes, this includes discussions with people I know that work or who have worked in front-line medical positions. Yes, how the wearer uses / fits a mask, touches / adjusts it, disposes / reuses, which type of masks and how much other protocols are followed will all influence the degree of mask effectiveness.
Yes, there are no large double-blind, peer-reviewed studies to support mask use (non that I could find anyway). I'm not a "chicken little". I do believe there has been far too much conflation by some of prudence to mean cowardice, panic or being overwrought.
Re: the video ... I found far too many instances of where the other two were putting words into Malone's mouth, or were quick to over-interpret something he said.
I really would love for someone who understands the deep bioscience to take a very hard look at their ppl virology claims. At face value, the assertions would be very concerning, and while I would prefer for them to be wrong, I would rather see analysis as to whether they are or not. Pseudoscience is based on a whole lot of very very credible information and takes a sudden turn that is virtually impossible for non-specialists to unravel.
My reading on ivermectin is that the concentrations required to be effective outside of in vitro would be extremely high. For what it's worth, here are a few articles. Science is an evolving understanding of complex systems. Time and testing will tell.
"Laboratory studies using monkey cells in a test tube (as opposed to clinical studies in human patients) have shown ivermectin can shut down the replication of SARS-CoV-2, the coronavirus that causes COVID-19, within 24-48 hours of exposure to the drug.
Ivermectin is thought to inhibit the virus by preventing viral proteins moving in and out of the host cell’s nucleus, which is essential for replication of the coronavirus.
The problem is this process requires very high concentrations of ivermectin – well above the recommended dose for humans. This means ivermectin’s virus-killing powers would be unlikely to be harnessed inside the human body."
(there are several linked references from within the article as well)
This next link is excellent - it delves into the molecular science w/out becoming incomprehensibly dense and there are three updates appended to the end showing promise.
https://blogs.sciencemag.org/pipeline/archives/2020/05/11/whats-up-with-ivermectin
Another very useful article:
mng