Which rationalists faced significant side-effects from COVID-19 vaccination?

1st shot of AstraZeneca: Fever for a week (shivering the first night and high fever the first day, then feeling feverish and temperature increased by 0.7 Celsius for about 7 days)

2nd shot: no side-effects

Pfizer. I'm not sure if I recall the first dose that well. There was some inflammation in my shoulder area, near the injection site. Kind of expected with all vaccines. Nothing else that made an impression on me.

The second dose was a bit worse. The inflammation resulted in some deeper, but mild soreness in the shoulder joint. I also noticed some mild lower-back soreness, perhaps in the kidney region. I did not bother taking any painkillers because it was pretty mild and didn't last very long. Maybe a couple of days, so not really significant. This was also within expectations.

Lately, I've been having palpitations, sometimes enough to cause some insomnia. Also some intermittent chest aches, but it's very mild. It was noticeable enough that I've been checking my heart rate more than usual. It seems a little elevated, even at rest, maybe in the 80 bpm range. I'm normally in the 70 range at rest, and can get down into the 60s when I'm very relaxed.

I thought nothing of it at first, because occasional palpitations due to stress are not unusual, and I had reasons to be stressed. But it's been unusually persistent for probably over a month now, even though I'm feeling less stressed than usual, which is more concerning. I don't recall exactly when it started, but it was definitely some time after the second dose. It probably started more than two weeks after (although I can't recall exactly) so maybe it's unrelated. It did not occur to me that this could be due to the vaccine until I saw that Dark Horse video.

Had Moderna. My first shot was worse than my second. The thing that surprised me -- I had a very specific kind of neuropathy that I like 90% recovered from in 2019, and some side-effects I had post-vaccination felt neuropathy-like. I don't know many people felt the same. I reported all of mine. They all went away in about 7-10 days, but it did happen.

I figured if non-replicating spike proteins can do this, then a virus that produces many more of them would do much worse. So I'm okay with having taken the vaccine. But I did have unusual side effects that may or may not have been related to previous nerve damage.

From another member that's also in the 25-100 karma range:

A family member of mine works in health care and has seen a representative sample of more than a thousand vaccinations and the side effects. Their impression is that the side effects are the strongest after Sputnik V, the weakest after Sinopharm, with mRNA-based vaccines being somewhere between the two. They reported no obvious cases of serious long-lasting side effects, only anecdotes of e.g. lasting loss of sense of smell that may or may not be linked to the vaccine. They has no experience in rationality.

I know about 16 vaccinated people I who I expect would have noticed+told me about easily noticeable >3 days side effects if they had occurred. 0/16 told me. Most mid-30s, two 60s. 40% W, 60% M. 80% basically healthy, 20% with significant health issues. Several groggy/sore/etc for a day, three very much so. Not sure about type distribution, though predominantly Pfizer.

Seems like you’re looking for anecdotes rather than data which strikes me as strange for a purported rationalist. The plural of anecdote may be data, but the quality of those data will be low. If it helps, I had one dose of AZ and had minimal side effects (slight headache, tiredness) that were gone in under 24 hours.

Anonymous post from a user with between 25 and 100 karma (range wide enough to be anonymizing):

"A few COVID vaccine data points for you, from the people in my close circle that I know about.

Me, M, early 40s. One dose of Pfizer. No side effects. Mother, late 60s, F. Two doses of Pfizer. No side effects. Father, early 70s, M. Two doses Astrazeneca. No side effects. Brother, early 40s, M. One dose Astrazeneca. Reported side effects. Thinks it may have made him react to a spice in a meal he made. Colleague, mid 40s, F. One dose Astrazeneca (I'm unsure on that). No major sure effects. Reported feeling grotty / wiped out for a day or two.

There are several other people in my circle who have had vaccine doses by now where I think it's quite likely I'd have heard of they'd had adverse reactions, but I've not had specific conversations with them about it. So I'd assume most of them have had no significant reactions."

Pfizer. First shot caused pain at the injection site that lasted about 24 hours. Second shot led to about twelve hours of what I would call moderately severe flu symptoms. Chills, exhaustion, headache (though one should note that the slightest breeze will give me a headache), brainfog. I basically slept all day, and woke up feeling fine the next morning.

My close family had 3 people receive 2x Pfizer, 1 2x Moderna, and 1 2x Novavax (part of a clinical trial). No side effects beyond muscle aches/fever/malaise for at most 24 hrs.

NB Novavax is not an mRNA vaccine; it's basically just the spike protein presented on an inactive substrate mixed with some preservatives/immune system agonists. A spike protein kebab, if you will.

J&J (1 shot): mild tiredness the next day, no other symptoms.

Moderna

1st shot:
Mild headache after waking up on next day, gone by evening. At that time I gave it a 80% probability of being connected to the vaccine. The pain in my shoulder was much more annoying and lasted for maybe 4 days (but no inflammation or anything else worrying).

2nd shot:
Got it 3 days ago. I got headache again so the one after the first dose was probably also a vaccine side-effect. This time it was significantly stronger. Nothing debilitating, but it made me relatively lethargic and not very eager to do things. The headache stayed with me for the entire day, but was gone next morning. Shoulder area-effects similar to the first dose but possibly milder?

I had fatigue, lightheadedness, and stiffness/aches for four or five days after the second shot. It wasn't that debilitating after the first two days but it sucked.

I don't regret getting the vaccine and I went in know I was probably going to be hit hard since I had similar (less intense) effects from the first shot.

Also... asking for anecdotes on a forum isn't a great way to gather data. A poll would be better, so you at least know how many people were fine.

I acknowledge how late I am. I experienced chronic illness which was close in time after my second shot from Moderna around May 20, 2021. I had typical moderate acute side effects (which were far below anaphylaxis), which gradually decreased to chronic fatigue symptoms, lasting over 6 months. There is no biological proof of a causal relationship. My GP noted t hat there was a plausible mechanism of immune overreaction and nervous system (PNS/SNS) imbalance. One reason for the long duration of chronic illness was my lack of resilience to deal with everyday life activities (ADL) with chronic fatigue most mornings, since I am young and live alone. I have never had a community to share this with, only a few close friends here and there. I have had insufficient  medical support, but this chapter of my life has drawn to a close. After recovering, I have made several steps to mitigate future episodes of chronic illness. I'd be happy to follow up on this.

I received the Moderna vaccine.

I didn't note any side effects after the first shot, except maybe some mild soreness around the injection site, and, if that, delayed about a day from when I received the shot.

But I had pretty noticeable side effects from the second shot – significant fatigue/lethargy, muscle aches, and general 'crumminess', and for about two days afterwards.

But, per your criteria, I had no "significant side-effects".