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Covid 'Mink variant' 2020-11-06T17:50:11.706Z

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Comment by henryaj on Why you should be using a retinoid · 2024-09-16T12:31:04.168Z · LW · GW

https://www.sciencedirect.com/science/article/pii/S1015958423001392 suggests that bright light might be causing the effect, not UV.

Comment by henryaj on Why you should be using a retinoid · 2024-09-16T12:26:30.538Z · LW · GW

That's an interesting paper! Although it seems a bit confounded - "Because eyes of mice and of human volunteers were not covered, we cannot exclude the possibility that solar/UV radiation to the eye affected the observed sexual behavior." Which would be interesting if true, suggesting that just being outside and getting UV light in the eyes would be the thing to do. I guess you note this at the end of your first comment.

What do you think about the potential skin aging effects of UV vs the potential health benefits?

Comment by henryaj on Why you should be using a retinoid · 2024-09-16T12:22:13.613Z · LW · GW

There's plenty of scientific evidence for the effectiveness of topical retinoids, going back several decades.

Comment by henryaj on Dear Self; We Need To Talk About Social Media · 2021-12-18T20:58:02.378Z · LW · GW

This is wonderful; thank you for writing it. Very much enjoyed the exposition of the "Quiet" state; have been trying out your advice of switching everything off and trying to slip into such a state and am enjoying what I've found there.

Comment by henryaj on Omicron Post #4 · 2021-12-09T10:03:40.628Z · LW · GW

Likewise, thanks for all you're doing Zvi.

Comment by henryaj on Omicron Post #4 · 2021-12-09T10:03:22.888Z · LW · GW

Sure enough, the UK has triggered its "Plan B" which mandates working from home for those who can, plus vaccine passports for big events. Perhaps suggests lockdowns coming in the new year.

Comment by henryaj on Omicron Variant Post #1: We’re F***ed, It’s Never Over · 2021-11-28T23:57:41.746Z · LW · GW

Do you know what kind of research Theodora's lab is actually doing? (She doesn't have a surname on Twitter so I can't find her). But I imagine research into spike protein mutants could just involve synthesising spike protein that has mutations and assaying the binding affinity of antibodies to the synthetic spike protein – not necessarily creating mutated viruses.

(undergrad biochemistry was a long time ago. I could well be wrong)

Comment by henryaj on Making Vaccine · 2021-02-06T13:55:15.725Z · LW · GW

I also don't understand her comments about the peptide 'not neutralising COVID in cell [culture]' - why would it? The peptide is just an antigen to get the body to raise an immune response; on its own it doesn't kill COVID.

Comment by henryaj on Covid 12/24: We’re F***ed, It’s Over · 2021-01-03T23:55:54.313Z · LW · GW

Not the OP so can't answer for him, but qualitatively the second (November) lockdown was quite different from the first (March) lockdown - much more leeway given on exercising outdoors, workplaces largely stayed open (even if people were working from home). In March, police officers would move people along if they were sitting on a park bench (as that's not exercise); the second time round things were much less strictly enforced. Rules around forming 'bubbles' with other households also didn't exist in March.

Tier 4 is essentially the same as the November lockdown but you can meet one other person outdoors.

Comment by henryaj on Covid 12/24: We’re F***ed, It’s Over · 2021-01-03T23:52:03.760Z · LW · GW

Cases went from about 20 on September 1 to 370 in  mid November.  Then they *dropped* to 213 before jumping up to 500.

The UK had a national lockdown in November, and lifted it at the start of December.

Comment by henryaj on Covid 12/24: We’re F***ed, It’s Over · 2020-12-28T13:35:58.007Z · LW · GW

Amazing how it differs by region. Here in the UK, anecdotally tests are pretty easy to come by and turned around rapidly - but are still restricted only to those with canonical COVID symptoms (fever/cough/change in sense of smell or taste).

Comment by henryaj on Covid 12/24: We’re F***ed, It’s Over · 2020-12-24T21:14:01.405Z · LW · GW

Meta: anyone else getting a bunch of broken images in this post?

Comment by henryaj on Covid 'Mink variant' · 2020-11-07T17:14:19.032Z · LW · GW

Thanks for the well-written and well-reasoned response!

Comment by henryaj on Peter's COVID Consolidated Brief for 29 March · 2020-03-30T12:58:41.801Z · LW · GW

Thanks for putting these updates together! :)

Comment by henryaj on Implementing an Idea-Management System · 2019-11-08T18:51:54.436Z · LW · GW
Um, isn't that basically a wiki?

Just picking up on this one point - I've used a bunch of personal wikis in the past; they just haven't stuck for me. Roam has some nice features around this, like backlinking (so just by idly putting something in [[brackets]] you're starting to collate a list of pages under that term) and searching through text to find 'missing links', neither of which I've seen in wikis.

Comment by henryaj on An Exercise in Applied Rationality: A New Apartment · 2018-07-09T01:40:03.970Z · LW · GW

Some thoughts:

  • buy nice homeware. The temptation is always to scrimp, but you're going to be using this stuff regularly for at least the length of your lease, and maybe years beyond that, so splash out on nice kitchenware (knives, nonstick pans, chopping boards, a rice cooker) and bathroom stuff (especially towels).
  • similarly, if there's stuff that needs fixing, do it right away - then you get the benefit of it for longer. For example, use draft excluder tape to seal the gaps around doors, fix radiators that don't work, rearrange furniture if you don't like the way it currently sits.
  • put your phone to charge somewhere away from your bed. (I've yet to be able to make this one stick, but maybe being somewhere new will help!)

Mostly moving into a new place really reveals the holes in my time (especially if you don't have a TV or haven't set one up yet), so try to be aware of where your time's going before you develop a routine and stop thinking about it critically.

Comment by henryaj on A LessWrong Crypto Autopsy · 2018-01-30T10:36:20.561Z · LW · GW
decided that people would probably use LaTeX more often than trying to use the dollar sign

Err... this seems like the kind of thing that *really* wouldn't stand up to user testing.

Comment by henryaj on What are you learning? · 2014-09-21T15:58:04.147Z · LW · GW

How do you Ankify knowledge like that? Or, to be specific, what's on the other side of those cards in Anki?

Comment by henryaj on What are you learning? · 2014-09-19T10:29:04.339Z · LW · GW

Interesting stuff. I've not had a great deal of success with OkC, but I tend to get bored of the dating site cycle – the few dates I've been on haven't been very exciting, and I tend to prefer meeting people in person (like at parties) as I find that more immediately engaging and exciting.

Could you link to your OkC profile? It'd be interesting to have a look at!

Comment by henryaj on Why don't you attend your local LessWrong meetup? / General meetup feedback · 2014-04-28T15:55:54.050Z · LW · GW

Filled in the form a moment ago.

Comment by henryaj on Want to have a CFAR instructor visit your LW group? · 2014-04-28T15:53:03.024Z · LW · GW

Cat, are you (or another instructor) planning any more trips to Europe? I'm sad to have missed out on your previous class!

Comment by henryaj on Best of Rationality Quotes, 2013 Edition · 2014-02-25T13:09:23.967Z · LW · GW

Great idea! I'm tempted to chop these up and put them into a mailing list - I feel they would be more useful in a one-quote-a-day format than in one big block.

Comment by henryaj on The mechanics of my recent productivity · 2014-01-09T10:23:54.610Z · LW · GW

Argh - just had a little twinge when I saw that you were born in 1989. You're the same age as me, but have done so much more!

Congratulations on reaching your goals. Reading this has reminded me that I ought to do the same.

Comment by henryaj on Happiness and Productivity. Living Alone. Living with Friends. Living with Family. · 2013-11-20T15:07:21.183Z · LW · GW

We have social norms of ... rewarding each other for doing good things (and a "gem economy" for this purpose)

I must hear more about this.

Comment by henryaj on Meetup : Comfort Zone Expansion outing - London · 2013-08-24T21:54:37.280Z · LW · GW

Sounds excellent. WIsh I could make it, but I've got a family thing to attend to that day. Next time, for sure!

Comment by henryaj on Meetup : Comfort Zone Expansion outing - London · 2013-08-24T12:29:00.954Z · LW · GW

I'm intrigued by this – comfort zone expansion strikes me as a very good idea, if done carefully; I'm thinking of things like Rejection Therapy, 'daygame' (making conversation/flirting with strangers in daytime settings, taking care not to become a harasser) and just generally being social.

In my forays with talking to strangers—an ongoing experiment!—I've found that Londoners are actually mostly very friendly, just with a veneer of coldness that needs breaking. I suspect this is true for people in most big cities, and is an adaptation to avoid the usual array of charity muggers, panhandlers and the like they encounter on an hourly basis.

What kind of activities are you planning?

Comment by henryaj on Optimizing for attractiveness · 2013-08-15T10:14:08.509Z · LW · GW

Great post! Those are both sources I really like. Some of Mark Manson (writer of PostMasculine)'s old material on Practical Pickup is good as well.

(I actually have written a long post meditating on this stuff that I'll be posting in a few days on LW Discussion, so look out for that. :P)

Did this ever get posted? I'd happily read through the draft and give you some feedback, if you like.

Comment by henryaj on Recent updates to gwern.net (2012-2013) · 2013-03-19T13:55:12.144Z · LW · GW

Nthing the "you are an inspiration" sentiment expressed here. This has reminded me that you should 'always be shipping'; always be doing stuff and making stuff.

What's your working environment like? You mention doing work for SI; is that at their offices or at home? I've been flirting with the idea of working part-time to pursue other projects in my spare time but I'm not sure I could hack being in a home office all day.

(And, if you don't mind me asking, how do you bankroll all this? Do you have a 'day job' per se?)

Comment by henryaj on Gender and Libido · 2011-07-05T18:02:26.954Z · LW · GW

One of the parts of this study involved quizzing men and women on their likelihood of accepting sex from a stranger using pictures of either an attractive or an unattractive person of the opposite sex to see if that affected the subject's likelihood of accepting the proposition, and found:

For the proposition by the attractive person, women were at 4.09 [out of 7] to 4.16 for men — just about a tie.

Which seems to suggest that, in this particular domain—sex with an attractive partner—men and women are equally desirous. It's the perceived danger (and lower sexual prowess) that the female subjects imagine come with the average proposer that makes them less likely to accept the offer than men.

This seems inconsistent with the notion that women are innately less desirous of sex than men; rather that they have more to lose from a casual encounter (as has been said) so are more guarded when accepting such a proposition.

Comment by henryaj on Gender and Libido · 2011-07-05T17:52:55.772Z · LW · GW

My understanding is that testosterone, gram for gram, affects the female body more potently than it does the male body. So bringing up a female's testosterone level to that of a male might not be dose-equivalent.

Or to put it another way: men's and women's physiologies are different. I'm not sure it's safe to assume that someone who has transitioned from female to male through hormone replacement is identical (and so directly comparable) to someone who was born male, so I'd question the validity of comparisons made between the two.